Fission Mailed is the one hundred fourteenth issue of the series.
Samus and Master Chief sneak down to the Ark, but realize that they don't know how to deactivate it. The High Prophet of Truth notices that no one is watching the Ark, and a large group of Covenant forces approach the heroes. Samus rolls into the Morph Ball, but Master Chief is surrounded. He covers for Samus by saying that he's acting alone, and is then knocked out. Oveur and the Arbiter find the Writer, who tells them that the Ark needs to be activated, not shut down, and convinces the two. A Brute holds up Master Chief and says that he has been captured, but doesn't notice the activated grenade in his hand.
- The title is a reference to a fake game over screen from Metal Gear Solid 2.
- The ending, in which a Brute holds a defeated Master Chief, who is holding a grenade, is a reference to the "Believe" diorama built for the release of Halo 3.
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