O is for Oprah is the eighty-eighth issue of the series.
Oprah Winfrey appears as the person who arrived to save Samus. She also appears with Dr. Phil. When Oveur asks her to rescue them, she instead giving him a cashmire scarf. This causes him to rudely insult her, and she suddenly morphs into a demon creature.
- This issues plot seems to be similar to a series of MadTV sketchs involving Oprah.
Fight and Escape
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